Entity Details

Primary name MK03_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ63844
EntryNameMK03_MOUSE
FullNameMitogen-activated protein kinase 3
TaxID10090
Evidenceevidence at protein level
Length380
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesMapk3

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001784 phosphotyrosine residue binding
GO:0001934 positive regulation of protein phosphorylation
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004707 MAP kinase activity
GO:0004708 MAP kinase kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005769 early endosome
GO:0005770 late endosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0006351 transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0006975 DNA damage induced protein phosphorylation
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007568 aging
GO:0009636 response to toxic substance
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0010759 positive regulation of macrophage chemotaxis
GO:0014032 neural crest cell development
GO:0016310 phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0019233 sensory perception of pain
GO:0019369 arachidonic acid metabolic process
GO:0019902 phosphatase binding
GO:0030278 regulation of ossification
GO:0030509 BMP signaling pathway
GO:0030641 regulation of cellular pH
GO:0030878 thyroid gland development
GO:0031143 pseudopodium
GO:0031281 positive regulation of cyclase activity
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032496 response to lipopolysaccharide
GO:0032872 regulation of stress-activated MAPK cascade
GO:0032991 protein-containing complex
GO:0033129 positive regulation of histone phosphorylation
GO:0034198 cellular response to amino acid starvation
GO:0034614 cellular response to reactive oxygen species
GO:0035066 positive regulation of histone acetylation
GO:0035556 intracellular signal transduction
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0042473 outer ear morphogenesis
GO:0042802 identical protein binding
GO:0043330 response to exogenous dsRNA
GO:0045727 positive regulation of translation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046697 decidualization
GO:0048538 thymus development
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0051216 cartilage development
GO:0051403 stress-activated MAPK cascade
GO:0051493 regulation of cytoskeleton organization
GO:0051973 positive regulation of telomerase activity
GO:0060020 Bergmann glial cell differentiation
GO:0060324 face development
GO:0060425 lung morphogenesis
GO:0060440 trachea formation
GO:0061308 cardiac neural crest cell development involved in heart development
GO:0065003 protein-containing complex assembly
GO:0070371 ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070498 interleukin-1-mediated signaling pathway
GO:0070849 response to epidermal growth factor
GO:0071260 cellular response to mechanical stimulus
GO:0071276 cellular response to cadmium ion
GO:0071356 cellular response to tumor necrosis factor
GO:0072584 caveolin-mediated endocytosis
GO:0090170 regulation of Golgi inheritance
GO:0097110 scaffold protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120041 positive regulation of macrophage proliferation
GO:1903351 cellular response to dopamine
GO:1904355 positive regulation of telomere capping
GO:1904417 positive regulation of xenophagy
GO:2000641 regulation of early endosome to late endosome transport
GO:2000657 negative regulation of apolipoprotein binding

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR003527 Mitogen-activated protein (MAP) kinase, conserved siteSiteConserved site
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR008349 Mitogen-activated protein (MAP) kinase, ERK1/2FamilyFamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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