Entity Details

Primary name CRK_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ64010
EntryNameCRK_MOUSE
FullNameAdapter molecule crk
TaxID10090
Evidenceevidence at protein level
Length304
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCrk

GO terms

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GOName
GO:0001764 neuron migration
GO:0001784 phosphotyrosine residue binding
GO:0001878 response to yeast
GO:0002685 regulation of leukocyte migration
GO:0005159 insulin-like growth factor receptor binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006629 lipid metabolic process
GO:0008092 cytoskeletal protein binding
GO:0008360 regulation of cell shape
GO:0009966 regulation of signal transduction
GO:0014911 positive regulation of smooth muscle cell migration
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0016358 dendrite development
GO:0017124 SH3 domain binding
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0019904 protein domain specific binding
GO:0021766 hippocampus development
GO:0021987 cerebral cortex development
GO:0030010 establishment of cell polarity
GO:0030036 actin cytoskeleton organization
GO:0030159 signaling receptor complex adaptor activity
GO:0030307 positive regulation of cell growth
GO:0030674 protein-macromolecule adaptor activity
GO:0031625 ubiquitin protein ligase binding
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0033628 regulation of cell adhesion mediated by integrin
GO:0035020 regulation of Rac protein signal transduction
GO:0035591 signaling adaptor activity
GO:0035685 helper T cell diapedesis
GO:0035728 response to hepatocyte growth factor
GO:0038026 reelin-mediated signaling pathway
GO:0042169 SH2 domain binding
GO:0042542 response to hydrogen peroxide
GO:0043087 regulation of GTPase activity
GO:0043393 regulation of protein binding
GO:0043621 protein self-association
GO:0045121 membrane raft
GO:0045309 protein phosphorylated amino acid binding
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway
GO:0050773 regulation of dendrite development
GO:0060326 cell chemotaxis
GO:0061045 negative regulation of wound healing
GO:0061847 response to cholecystokinin
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071732 cellular response to nitric oxide
GO:0090630 activation of GTPase activity
GO:0097110 scaffold protein binding
GO:0098749 cerebellar neuron development
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901652 response to peptide
GO:1902531 regulation of intracellular signal transduction
GO:1990090 cellular response to nerve growth factor stimulus
GO:1990314 cellular response to insulin-like growth factor stimulus
GO:1990782 protein tyrosine kinase binding
GO:1990859 cellular response to endothelin
GO:2000146 negative regulation of cell motility
GO:2000404 regulation of T cell migration

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR035457 CRK, N-terminal SH3 domainDomainDomain
IPR035458 CRK, C-terminal SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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