Entity Details

Primary name GLRA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ64018
EntryNameGLRA1_MOUSE
FullNameGlycine receptor subunit alpha-1
TaxID10090
Evidenceevidence at protein level
Length457
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGlra1

GO terms

Show/Hide Table
GOName
GO:0001508 action potential
GO:0001964 startle response
GO:0002087 regulation of respiratory gaseous exchange by nervous system process
GO:0004888 transmembrane signaling receptor activity
GO:0005783 endoplasmic reticulum
GO:0005887 integral component of plasma membrane
GO:0006811 ion transport
GO:0006820 anion transport
GO:0006821 chloride transport
GO:0006936 muscle contraction
GO:0007165 signal transduction
GO:0007218 neuropeptide signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007340 acrosome reaction
GO:0007601 visual perception
GO:0007628 adult walking behavior
GO:0008270 zinc ion binding
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016594 glycine binding
GO:0016933 extracellularly glycine-gated ion channel activity
GO:0016934 extracellularly glycine-gated chloride channel activity
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0030977 taurine binding
GO:0034220 ion transmembrane transport
GO:0034707 chloride channel complex
GO:0042391 regulation of membrane potential
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043200 response to amino acid
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0043576 regulation of respiratory gaseous exchange
GO:0044305 calyx of Held
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0050877 nervous system process
GO:0050884 neuromuscular process controlling posture
GO:0050905 neuromuscular process
GO:0051970 negative regulation of transmission of nerve impulse
GO:0060012 synaptic transmission, glycinergic
GO:0060013 righting reflex
GO:0060077 inhibitory synapse
GO:0060080 inhibitory postsynaptic potential
GO:0071230 cellular response to amino acid stimulus
GO:0071294 cellular response to zinc ion
GO:0071361 cellular response to ethanol
GO:0097305 response to alcohol
GO:0098690 glycinergic synapse
GO:0099056 integral component of presynaptic membrane
GO:0099060 integral component of postsynaptic specialization membrane
GO:1902476 chloride transmembrane transport
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:2000344 positive regulation of acrosome reaction

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane
Cell projection
Perikaryon

Domains

Show/Hide Table
DomainNameCategoryType
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alphaFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR008127 Glycine receptor alphaFamilyFamily
IPR008128 Glycine receptor alpha1FamilyFamily
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GLRA1_MOUSEHUWE1_MOUSEBioGRID30721695 details