Entity Details

Primary name MCF2L_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ64096
EntryNameMCF2L_MOUSE
FullNameGuanine nucleotide exchange factor DBS
TaxID10090
Evidenceevidence at protein level
Length1149
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005545 1-phosphatidylinositol binding
GO:0005737 cytoplasm
GO:0007266 Rho protein signal transduction
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0019898 extrinsic component of membrane
GO:0030027 lamellipodium
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035091 phosphatidylinositol binding
GO:0045944 positive regulation of transcription by RNA polymerase II

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001251 CRAL-TRIO lipid binding domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR035532 DBS, SH3 domainDomainDomain
IPR035534 DBS, PH domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036865 CRAL-TRIO lipid binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions