Entity Details

Primary name IRF4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ64287
EntryNameIRF4_MOUSE
FullNameInterferon regulatory factor 4
TaxID10090
Evidenceevidence at protein level
Length450
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesIrf4

GO terms

Show/Hide Table
GOName
GO:0000786 nucleosome
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002376 immune system process
GO:0003700 DNA-binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0032733 positive regulation of interleukin-10 production
GO:0032736 positive regulation of interleukin-13 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0034122 negative regulation of toll-like receptor signaling pathway
GO:0042832 defense response to protozoan
GO:0043011 myeloid dendritic cell differentiation
GO:0043388 positive regulation of DNA binding
GO:0043565 sequence-specific DNA binding
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0072540 T-helper 17 cell lineage commitment
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001346 Interferon regulatory factor DNA-binding domainDomainDomain
IPR008984 SMAD/FHA domain superfamilyFamilyHomologous superfamily
IPR017855 SMAD-like domain superfamilyFamilyHomologous superfamily
IPR019471 Interferon regulatory factor-3DomainDomain
IPR019817 Interferon regulatory factor, conserved siteSiteConserved site
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table