Entity Details

Primary name ZEB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ64318
EntryNameZEB1_MOUSE
FullNameZinc finger E-box-binding homeobox 1
TaxID10090
Evidenceevidence at protein level
Length1117
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesZeb1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007389 pattern specification process
GO:0007417 central nervous system development
GO:0008285 negative regulation of cell population proliferation
GO:0010464 regulation of mesenchymal cell proliferation
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0030154 cell differentiation
GO:0030857 negative regulation of epithelial cell differentiation
GO:0033081 regulation of T cell differentiation in thymus
GO:0043565 sequence-specific DNA binding
GO:0045602 negative regulation of endothelial cell differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048513 animal organ development
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048598 embryonic morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
GO:0048752 semicircular canal morphogenesis
GO:0048856 anatomical structure development
GO:0051150 regulation of smooth muscle cell differentiation
GO:0051216 cartilage development
GO:0070888 E-box binding
GO:0071230 cellular response to amino acid stimulus
GO:0090103 cochlea morphogenesis

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR008598 Drought induced 19 protein type, zinc-binding domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions