Entity Details

Primary name BPI_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ67E05
EntryNameBPI_MOUSE
FullNameBactericidal permeability-increasing protein
TaxID10090
Evidenceevidence at protein level
Length483
SequenceStatuscomplete
DateCreated2008-12-16
DateModified2021-06-02

Ontological Relatives

GenesBpi

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006955 immune response
GO:0010494 cytoplasmic stress granule
GO:0016020 membrane
GO:0019731 antibacterial humoral response
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032715 negative regulation of interleukin-6 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0042742 defense response to bacterium
GO:0043031 negative regulation of macrophage activation
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0071222 cellular response to lipopolysaccharide

Subcellular Location

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Subcellular Location
Cytoplasmic granule membrane
Secreted

Domains

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DomainNameCategoryType
IPR001124 Lipid-binding serum glycoprotein, C-terminalDomainDomain
IPR017942 Lipid-binding serum glycoprotein, N-terminalDomainDomain
IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamilyFamilyHomologous superfamily
IPR030181 Bactericidal permeability-increasing proteinFamilyFamily
IPR030675 Lipid binding protein BPI/LBPFamilyFamily
IPR032942 BPI/LBP/Plunc familyFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink