Entity Details

Primary name GRM7_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ68ED2
EntryNameGRM7_MOUSE
FullNameMetabotropic glutamate receptor 7
TaxID10090
Evidenceevidence at protein level
Length915
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesGrm7

GO terms

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GOName
GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0001642 group III metabotropic glutamate receptor activity
GO:0001661 conditioned taste aversion
GO:0001662 behavioral fear response
GO:0005245 voltage-gated calcium channel activity
GO:0005246 calcium channel regulator activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0005938 cell cortex
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO:0007216 G protein-coupled glutamate receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007605 sensory perception of sound
GO:0007613 memory
GO:0007614 short-term memory
GO:0008066 glutamate receptor activity
GO:0008306 associative learning
GO:0009986 cell surface
GO:0010855 adenylate cyclase inhibitor activity
GO:0014050 negative regulation of glutamate secretion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016595 glutamate binding
GO:0019226 transmission of nerve impulse
GO:0030165 PDZ domain binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030534 adult behavior
GO:0032279 asymmetric synapse
GO:0032991 protein-containing complex
GO:0033555 multicellular organismal response to stress
GO:0042734 presynaptic membrane
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043195 terminal bouton
GO:0043198 dendritic shaft
GO:0043235 receptor complex
GO:0043524 negative regulation of neuron apoptotic process
GO:0043679 axon terminus
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0048306 calcium-dependent protein binding
GO:0048786 presynaptic active zone
GO:0048787 presynaptic active zone membrane
GO:0050877 nervous system process
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0070905 serine binding
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099056 integral component of presynaptic membrane
GO:0099059 integral component of presynaptic active zone membrane
GO:1901214 regulation of neuron death
GO:2000300 regulation of synaptic vesicle exocytosis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000162 GPCR, family 3, metabotropic glutamate receptorFamilyFamily
IPR000337 GPCR, family 3FamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR001883 GPCR, family 3, metabotropic glutamate receptor 7FamilyFamily
IPR011500 GPCR, family 3, nine cysteines domainDomainDomain
IPR017978 GPCR family 3, C-terminalDomainDomain
IPR017979 GPCR, family 3, conserved siteSiteConserved site
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily
IPR038550 GPCR, family 3, nine cysteines domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GRM7_MOUSESTXB1_MOUSEDIP19822743 details