Entity Details

Primary name GIT1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ68FF6
EntryNameGIT1_MOUSE
FullNameARF GTPase-activating protein GIT1
TaxID10090
Evidenceevidence at protein level
Length770
SequenceStatuscomplete
DateCreated2005-09-13
DateModified2021-06-02

Ontological Relatives

GenesGit1

GO terms

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GOName
GO:0001771 immunological synapse formation
GO:0001957 intramembranous ossification
GO:0005096 GTPase activator activity
GO:0005739 mitochondrion
GO:0005768 endosome
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0007420 brain development
GO:0007626 locomotory behavior
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0031267 small GTPase binding
GO:0032013 negative regulation of ARF protein signal transduction
GO:0032465 regulation of cytokinesis
GO:0032691 negative regulation of interleukin-1 beta production
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043015 gamma-tubulin binding
GO:0044305 calyx of Held
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045454 cell redox homeostasis
GO:0045820 negative regulation of glycolytic process
GO:0046872 metal ion binding
GO:0048013 ephrin receptor signaling pathway
GO:0048666 neuron development
GO:0060996 dendritic spine development
GO:0061743 motor learning
GO:0071222 cellular response to lipopolysaccharide
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0090063 positive regulation of microtubule nucleation
GO:0097431 mitotic spindle pole
GO:0098794 postsynapse
GO:0098879 structural constituent of postsynaptic specialization
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099171 presynaptic modulation of chemical synaptic transmission
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane
GO:0106015 negative regulation of inflammatory response to wounding
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2000646 positive regulation of receptor catabolic process

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001164 Arf GTPase activating proteinDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR013724 GIT, Spa2 homology (SHD) domainDomainDomain
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR022018 ARF GTPase-activating protein GIT1, C-terminalDomainDomain
IPR032352 Arf GTPase-activating protein GIT1/2, coiled-coil domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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