Entity Details

Primary name APEX2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ68G58
EntryNameAPEX2_MOUSE
FullNameDNA-(apurinic or apyrimidinic site) endonuclease 2
TaxID10090
Evidenceevidence at protein level
Length516
SequenceStatuscomplete
DateCreated2005-08-30
DateModified2021-06-02

Ontological Relatives

GenesApex2

GO terms

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GOName
GO:0001650 fibrillar center
GO:0003677 DNA binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519 endonuclease activity
GO:0004528 phosphodiesterase I activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0006284 base-excision repair
GO:0006310 DNA recombination
GO:0007049 cell cycle
GO:0008270 zinc ion binding
GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity
GO:0043231 intracellular membrane-bounded organelle

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR004808 AP endonuclease 1FamilyFamily
IPR005135 Endonuclease/exonuclease/phosphataseDomainDomain
IPR010666 Zinc finger, GRF-typeDomainDomain
IPR020847 AP endonuclease 1, binding siteSiteBinding site
IPR036691 Endonuclease/exonuclease/phosphatase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink