Entity Details

Primary name PREX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ69ZK0
EntryNamePREX1_MOUSE
FullNamePhosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
TaxID10090
Evidenceevidence at protein level
Length1650
SequenceStatuscomplete
DateCreated2007-06-26
DateModified2021-06-02

Ontological Relatives

GenesPrex1

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005543 phospholipid binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0030217 T cell differentiation
GO:0030335 positive regulation of cell migration
GO:0030426 growth cone
GO:0030593 neutrophil chemotaxis
GO:0030833 regulation of actin filament polymerization
GO:0035556 intracellular signal transduction
GO:0043198 dendritic shaft
GO:0043547 positive regulation of GTPase activity
GO:0045785 positive regulation of cell adhesion
GO:0048471 perinuclear region of cytoplasm
GO:0050773 regulation of dendrite development
GO:0072593 reactive oxygen species metabolic process
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000591 DEP domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001478 PDZ domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PREX1_MOUSEABI1_MOUSEIntAct15102471 details