Entity Details

Primary name SLX4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6P1D7
EntryNameSLX4_MOUSE
FullNameStructure-specific endonuclease subunit SLX4
TaxID10090
Evidenceevidence at protein level
Length1565
SequenceStatuscomplete
DateCreated2009-09-22
DateModified2021-06-02

Ontological Relatives

GenesSlx4

GO terms

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GOName
GO:0000706 meiotic DNA double-strand break processing
GO:0000712 resolution of meiotic recombination intermediates
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0003677 DNA binding
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0008047 enzyme activator activity
GO:0008821 crossover junction endodeoxyribonuclease activity
GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing
GO:0017108 5'-flap endonuclease activity
GO:0019899 enzyme binding
GO:0030054 cell junction
GO:0033557 Slx1-Slx4 complex
GO:0036297 interstrand cross-link repair
GO:0046872 metal ion binding
GO:0048257 3'-flap endonuclease activity
GO:0048476 Holliday junction resolvase complex
GO:0061820 telomeric D-loop disassembly
GO:0070522 ERCC4-ERCC1 complex
GO:0072429 response to intra-S DNA damage checkpoint signaling
GO:0090656 t-circle formation
GO:1904357 negative regulation of telomere maintenance via telomere lengthening
GO:1904431 positive regulation of t-circle formation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR006642 Rad18, zinc finger UBZ4-typeDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR018574 Structure-specific endonuclease subunit Slx4FamilyFamily

Diseases

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