Entity Details

Primary name KDM2B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6P1G2
EntryNameKDM2B_MOUSE
FullNameLysine-specific demethylase 2B
TaxID10090
Evidenceevidence at protein level
Length1309
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesKdm2b

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003712 transcription coregulator activity
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006482 protein demethylation
GO:0007283 spermatogenesis
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0021555 midbrain-hindbrain boundary morphogenesis
GO:0021592 fourth ventricle development
GO:0021670 lateral ventricle development
GO:0021678 third ventricle development
GO:0021993 initiation of neural tube closure
GO:0030307 positive regulation of cell growth
GO:0030900 forebrain development
GO:0030901 midbrain development
GO:0030902 hindbrain development
GO:0031519 PcG protein complex
GO:0032452 histone demethylase activity
GO:0035518 histone H2A monoubiquitination
GO:0043524 negative regulation of neuron apoptotic process
GO:0045322 unmethylated CpG binding
GO:0048596 embryonic camera-type eye morphogenesis
GO:0051864 histone demethylase activity (H3-K36 specific)
GO:0070544 histone H3-K36 demethylation
GO:1902459 positive regulation of stem cell population maintenance
GO:2000178 negative regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001810 F-box domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002857 Zinc finger, CXXC-typeDomainDomain
IPR003347 JmjC domainDomainDomain
IPR006553 Leucine-rich repeat, cysteine-containing subtypeRepeatRepeat
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR041070 Jumonji, helical domainDomainDomain
IPR041667 Cupin-like domain 8DomainDomain

Diseases

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