Entity Details

Primary name U520_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6P4T2
EntryNameU520_MOUSE
FullNameU5 small nuclear ribonucleoprotein 200 kDa helicase
TaxID10090
Evidenceevidence at protein level
Length2136
SequenceStatuscomplete
DateCreated2013-04-03
DateModified2021-06-02

Ontological Relatives

GenesSnrnp200

GO terms

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GOName
GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0042802 identical protein binding
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071005 U2-type precatalytic spliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071013 catalytic step 2 spliceosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR004179 Sec63 domainDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR041094 Brr2, N-terminal helicase PWI domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
U520_MOUSEITB3_MOUSEBioGRID30333137 details