Entity Details

Primary name SNX6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6P8X1
EntryNameSNX6_MOUSE
FullNameSorting nexin-6
TaxID10090
Evidenceevidence at protein level
Length406
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesSnx6

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005829 cytosol
GO:0006886 intracellular protein transport
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030904 retromer complex
GO:0031901 early endosome membrane
GO:0034452 dynactin binding
GO:0034713 type I transforming growth factor beta receptor binding
GO:0035091 phosphatidylinositol binding
GO:0042147 retrograde transport, endosome to Golgi
GO:0042803 protein homodimerization activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0097422 tubular endosome
GO:1904646 cellular response to amyloid-beta

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Early endosome membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001683 Phox homologyDomainDomain
IPR014637 Sorting nexin-5/6/32FamilyFamily
IPR015404 Sorting nexin Vps5-like, C-terminalDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR028657 Sorting nexin-6FamilyFamily
IPR036871 PX domain superfamilyFamilyHomologous superfamily
IPR042136 SNX6, PX domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SNX6_MOUSEMTR1L_MOUSEIntAct21858214 details
SNX6_MOUSEGIT1_MOUSEBioGRID18523162 32325033 details