Entity Details

Primary name ARHGI_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6P9R4
EntryNameARHGI_MOUSE
FullNameRho guanine nucleotide exchange factor 18
TaxID10090
Evidenceevidence at protein level
Length1405
SequenceStatuscomplete
DateCreated2008-06-10
DateModified2021-06-02

Ontological Relatives

GenesArhgef18

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0007264 small GTPase mediated signal transduction
GO:0008360 regulation of cell shape
GO:0016324 apical plasma membrane
GO:0030036 actin cytoskeleton organization
GO:0035023 regulation of Rho protein signal transduction
GO:0045177 apical part of cell
GO:0046872 metal ion binding
GO:0051497 negative regulation of stress fiber assembly
GO:0150105 protein localization to cell-cell junction

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR037744 ARHGEF18, PH domainDomainDomain
IPR041020 ARHGEF1-like, PH domainDomainDomain

Diseases

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Interactions

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