Entity Details

Primary name HLTF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6PCN7
EntryNameHLTF_MOUSE
FullNameHelicase-like transcription factor
TaxID10090
Evidenceevidence at protein level
Length1003
SequenceStatuscomplete
DateCreated2005-03-01
DateModified2021-06-02

Ontological Relatives

GenesHltf

GO terms

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GOName
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006325 chromatin organization
GO:0008094 ATPase, acting on DNA
GO:0008270 zinc ion binding
GO:0031625 ubiquitin protein ligase binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0061630 ubiquitin protein ligase activity
GO:0070615 nucleosome-dependent ATPase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014905 HIRAN domainDomainDomain
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
HLTF_MOUSEANXA2_MOUSEBioGRID, IntAct23415230 details
HLTF_MOUSES10AA_MOUSEBioGRID, IntAct23415230 32325033 details
HLTF_MOUSECDX2_MOUSEBioGRID, IntAct20211142 details