Entity Details

Primary name SMCA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6PGB8
EntryNameSMCA1_MOUSE
FullNameProbable global transcription activator SNF2L1
TaxID10090
Evidenceevidence at protein level
Length1046
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesSmarca1

GO terms

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GOName
GO:0000785 chromatin
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006338 chromatin remodeling
GO:0006355 regulation of transcription, DNA-templated
GO:0007420 brain development
GO:0008094 ATPase, acting on DNA
GO:0008134 transcription factor binding
GO:0016589 NURF complex
GO:0030182 neuron differentiation
GO:0031491 nucleosome binding
GO:0036310 ATP-dependent DNA/DNA annealing activity
GO:0043044 ATP-dependent chromatin remodeling
GO:0043231 intracellular membrane-bounded organelle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070615 nucleosome-dependent ATPase activity
GO:0090537 CERF complex
GO:2000177 regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001005 SANT/Myb domainDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR015194 ISWI, HAND domainDomainDomain
IPR015195 SLIDE domainDomainDomain
IPR017884 SANT domainDomainDomain
IPR020838 DBINO domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036306 ISWI, HAND domain superfamilyFamilyHomologous superfamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SMCA1_MOUSEEWS_MOUSEBioGRID, IntAct20211142 details