Entity Details

Primary name SORT_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6PHU5
EntryNameSORT_MOUSE
FullNameSortilin
TaxID10090
Evidenceevidence at protein level
Length825
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GenesSort1

GO terms

Show/Hide Table
GOName
GO:0001503 ossification
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006622 protein targeting to lysosome
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006895 Golgi to endosome transport
GO:0006897 endocytosis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007275 multicellular organism development
GO:0008333 endosome to lysosome transport
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0010465 nerve growth factor receptor activity
GO:0010468 regulation of gene expression
GO:0014902 myotube differentiation
GO:0016021 integral component of membrane
GO:0016050 vesicle organization
GO:0019899 enzyme binding
GO:0030136 clathrin-coated vesicle
GO:0030140 trans-Golgi network transport vesicle
GO:0030379 neurotensin receptor activity, non-G protein-coupled
GO:0030425 dendrite
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0031965 nuclear membrane
GO:0032509 endosome transport via multivesicular body sorting pathway
GO:0032580 Golgi cisterna membrane
GO:0032868 response to insulin
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
GO:0045599 negative regulation of fat cell differentiation
GO:0046323 glucose import
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048227 plasma membrane to endosome transport
GO:0048406 nerve growth factor binding
GO:0048471 perinuclear region of cytoplasm
GO:0051005 negative regulation of lipoprotein lipase activity
GO:0090160 Golgi to lysosome transport
GO:1904037 positive regulation of epithelial cell apoptotic process
GO:1905394 retromer complex binding

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Endoplasmic reticulum membrane
Endosome membrane
Golgi apparatus
Lysosome membrane
Nucleus membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR006581 VPS10DomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR031777 Sortilin, C-terminalDomainDomain
IPR031778 Sortilin, N-terminalDomainDomain

Diseases

Show/Hide Table