Entity Details

Primary name KMT2B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08550
EntryNameKMT2B_MOUSE
FullNameHistone-lysine N-methyltransferase 2B
TaxID10090
Evidenceevidence at protein level
Length2713
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesKmt2b

GO terms

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GOName
GO:0001541 ovarian follicle development
GO:0005634 nucleus
GO:0007613 memory
GO:0008270 zinc ion binding
GO:0009994 oocyte differentiation
GO:0016458 gene silencing
GO:0030728 ovulation
GO:0034968 histone lysine methylation
GO:0035097 histone methyltransferase complex
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0044648 histone H3-K4 dimethylation
GO:0045322 unmethylated CpG binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051568 histone H3-K4 methylation
GO:0051569 regulation of histone H3-K4 methylation
GO:0080182 histone H3-K4 trimethylation
GO:0097692 histone H3-K4 monomethylation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002857 Zinc finger, CXXC-typeDomainDomain
IPR003616 Post-SET domainDomainDomain
IPR003888 FY-rich, N-terminalDomainDomain
IPR003889 FY-rich, C-terminalDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR016569 Methyltransferase, trithoraxFamilyFamily
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR034732 Extended PHD (ePHD) domainDomainDomain
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR041959 KMT2B, ePHD domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
KMT2B_MOUSEH33_MOUSEBioGRID17707229 details
KMT2B_MOUSERBTN2_MOUSEBioGRID26764384 details