Entity Details

Primary name NPCL1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6T3U4
EntryNameNPCL1_MOUSE
FullNameNPC1-like intracellular cholesterol transporter 1
TaxID10090
Evidenceevidence at protein level
Length1333
SequenceStatuscomplete
DateCreated2005-08-30
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0005319 lipid transporter activity
GO:0006695 cholesterol biosynthetic process
GO:0016324 apical plasma membrane
GO:0030299 intestinal cholesterol absorption
GO:0030301 cholesterol transport
GO:0031267 small GTPase binding
GO:0031489 myosin V binding
GO:0031526 brush border membrane
GO:0042157 lipoprotein metabolic process
GO:0042632 cholesterol homeostasis
GO:0044214 spanning component of plasma membrane
GO:0071501 cellular response to sterol depletion

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR000731 Sterol-sensing domainDomainDomain
IPR003392 Protein patched/dispatchedFamilyFamily
IPR004765 NPC1-likeFamilyFamily
IPR032190 Niemann-Pick C1, N-terminalDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink