Entity Details

Primary name EYA2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08575
EntryNameEYA2_MOUSE
FullNameEyes absent homolog 2
TaxID10090
Evidenceevidence at protein level
Length532
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesEya2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006470 protein dephosphorylation
GO:0007275 multicellular organism development
GO:0008134 transcription factor binding
GO:0014706 striated muscle tissue development
GO:0016576 histone dephosphorylation
GO:0030154 cell differentiation
GO:0045739 positive regulation of DNA repair
GO:0048856 anatomical structure development
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097345 mitochondrial outer membrane permeabilization
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR006545 EYA domainDomainDomain
IPR028472 Eyes absent familyFamilyFamily
IPR028473 Eyes absent homologue 2FamilyFamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR038102 EYA domain superfamilyFamilyHomologous superfamily
IPR042577 EYA domain, metazoanDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
EYA2_MOUSESIX4_MOUSEUniProt10490620 details
EYA2_MOUSESHRPN_MOUSEBioGRID, IntAct20956555 details
EYA2_MOUSEHOIL1_MOUSEIntAct20956555 details