Entity Details

Primary name NTRK3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6VNS1
EntryNameNTRK3_MOUSE
FullNameNT-3 growth factor receptor
TaxID10090
Evidenceevidence at protein level
Length825
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesNtrk3

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001764 neuron migration
GO:0001933 negative regulation of protein phosphorylation
GO:0002039 p53 binding
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005004 GPI-linked ephrin receptor activity
GO:0005030 neurotrophin receptor activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007507 heart development
GO:0007623 circadian rhythm
GO:0008284 positive regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010976 positive regulation of neuron projection development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 membrane
GO:0019227 neuronal action potential propagation
GO:0022011 myelination in peripheral nervous system
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0032148 activation of protein kinase B activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033674 positive regulation of kinase activity
GO:0042490 mechanoreceptor differentiation
GO:0043065 positive regulation of apoptotic process
GO:0043121 neurotrophin binding
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0048665 neuron fate specification
GO:0048691 positive regulation of axon extension involved in regeneration
GO:0048712 negative regulation of astrocyte differentiation
GO:0050927 positive regulation of positive chemotaxis
GO:0051896 regulation of protein kinase B signaling
GO:0051965 positive regulation of synapse assembly
GO:0060548 negative regulation of cell death
GO:0070306 lens fiber cell differentiation
GO:0090630 activation of GTPase activity
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099151 regulation of postsynaptic density assembly
GO:1905606 regulation of presynapse assembly
GO:1990090 cellular response to nerve growth factor stimulus
GO:2000251 positive regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000372 Leucine-rich repeat N-terminal domainDomainDomain
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR002011 Tyrosine-protein kinase, receptor class II, conserved siteSiteConserved site
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020446 Tyrosine-protein kinase, neurotrophic receptor, type 3FamilyFamily
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR020777 Tyrosine-protein kinase, neurotrophic receptorFamilyFamily
IPR031635 Tyrosine-protein kinase receptor NTRK, C2-Ig-like domainDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NTRK3_MOUSEDOK6_MOUSEBioGRID, IntAct20565848 details