Entity Details

Primary name TIAM2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6ZPF3
EntryNameTIAM2_MOUSE
FullNameRho guanine nucleotide exchange factor TIAM2
TaxID10090
Evidenceevidence at protein level
Length1715
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesTiam2

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0007264 small GTPase mediated signal transduction
GO:0016020 membrane
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0030426 growth cone
GO:0043204 perikaryon
GO:0045202 synapse
GO:0050772 positive regulation of axonogenesis
GO:0090630 activation of GTPase activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Perikaryon

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001478 PDZ domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR003116 Raf-like Ras-bindingDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR040655 TIAM1, CC-Ex domainDomainDomain
IPR043537 Tiam1/Tiam2/Protein still lifeFamilyFamily

Diseases

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