Entity Details

Primary name KDM1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6ZQ88
EntryNameKDM1A_MOUSE
FullNameLysine-specific histone demethylase 1A
TaxID10090
Evidenceevidence at protein level
Length853
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesKdm1a

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002039 p53 binding
GO:0002052 positive regulation of neuroblast proliferation
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006342 chromatin silencing
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006482 protein demethylation
GO:0008134 transcription factor binding
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0010725 regulation of primitive erythrocyte differentiation
GO:0010976 positive regulation of neuron projection development
GO:0016491 oxidoreductase activity
GO:0019899 enzyme binding
GO:0021983 pituitary gland development
GO:0030154 cell differentiation
GO:0030374 nuclear receptor coactivator activity
GO:0030851 granulocyte differentiation
GO:0032091 negative regulation of protein binding
GO:0032451 demethylase activity
GO:0032452 histone demethylase activity
GO:0032453 histone demethylase activity (H3-K4 specific)
GO:0032454 histone demethylase activity (H3-K9 specific)
GO:0032991 protein-containing complex
GO:0033169 histone H3-K9 demethylation
GO:0033184 positive regulation of histone ubiquitination
GO:0034644 cellular response to UV
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific)
GO:0034720 histone H3-K4 demethylation
GO:0035563 positive regulation of chromatin binding
GO:0043426 MRF binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045654 positive regulation of megakaryocyte differentiation
GO:0045793 positive regulation of cell size
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046098 guanine metabolic process
GO:0050660 flavin adenine dinucleotide binding
GO:0050681 androgen receptor binding
GO:0050767 regulation of neurogenesis
GO:0050768 negative regulation of neurogenesis
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051572 negative regulation of histone H3-K4 methylation
GO:0051573 negative regulation of histone H3-K9 methylation
GO:0055001 muscle cell development
GO:0061752 telomeric repeat-containing RNA binding
GO:0071480 cellular response to gamma radiation
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1903827 regulation of cellular protein localization
GO:1990138 neuron projection extension
GO:1990391 DNA repair complex
GO:1990841 promoter-specific chromatin binding
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2000648 positive regulation of stem cell proliferation

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR002937 Amine oxidaseDomainDomain
IPR007526 SWIRM domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017366 Histone lysine-specific demethylaseFamilyFamily
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table