Entity Details

Primary name TOPB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6ZQF0
EntryNameTOPB1_MOUSE
FullNameDNA topoisomerase 2-binding protein 1
TaxID10090
Evidenceevidence at protein level
Length1515
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesTopbp1

GO terms

Show/Hide Table
GOName
GO:0000794 condensed nuclear chromosome
GO:0000922 spindle pole
GO:0001673 male germ cell nucleus
GO:0003677 DNA binding
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005886 plasma membrane
GO:0006270 DNA replication initiation
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0007131 reciprocal meiotic recombination
GO:0010212 response to ionizing radiation
GO:0015629 actin cytoskeleton
GO:0016604 nuclear body
GO:0016605 PML body
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle

Subcellular Location

Show/Hide Table
Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001357 BRCT domainDomainDomain
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

3 interactions