Entity Details

Primary name SYNE2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6ZWQ0
EntryNameSYNE2_MOUSE
FullNameNesprin-2
TaxID10090
Evidenceevidence at protein level
Length6874
SequenceStatuscomplete
DateCreated2010-03-23
DateModified2021-06-02

Ontological Relatives

GenesSyne2

GO terms

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GOName
GO:0003779 actin binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005925 focal adhesion
GO:0006998 nuclear envelope organization
GO:0007097 nuclear migration
GO:0007163 establishment or maintenance of cell polarity
GO:0010761 fibroblast migration
GO:0016021 integral component of membrane
GO:0016529 sarcoplasmic reticulum
GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration
GO:0030016 myofibril
GO:0030018 Z disc
GO:0030335 positive regulation of cell migration
GO:0031022 nuclear migration along microfilament
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031965 nuclear membrane
GO:0031981 nuclear lumen
GO:0033017 sarcoplasmic reticulum membrane
GO:0034504 protein localization to nucleus
GO:0034993 meiotic nuclear membrane microtubule tethering complex
GO:0045111 intermediate filament cytoskeleton
GO:0051015 actin filament binding
GO:0051642 centrosome localization
GO:0140444 cytoskeleton-nuclear membrane anchor activity
GO:1902017 regulation of cilium assembly

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Mitochondrion
Nucleus
Nucleus outer membrane
Sarcoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001715 Calponin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR012315 KASH domainDomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR030266 Nesprin-2FamilyFamily
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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