Entity Details

Primary name SYNE1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ6ZWR6
EntryNameSYNE1_MOUSE
FullNameNesprin-1
TaxID10090
Evidenceevidence at protein level
Length8799
SequenceStatuscomplete
DateCreated2010-03-23
DateModified2021-06-02

Ontological Relatives

GenesSyne1

GO terms

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GOName
GO:0000932 P-body
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003779 actin binding
GO:0005102 signaling receptor binding
GO:0005521 lamin binding
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005819 spindle
GO:0007030 Golgi organization
GO:0007097 nuclear migration
GO:0007283 spermatogenesis
GO:0016021 integral component of membrane
GO:0019899 enzyme binding
GO:0030017 sarcomere
GO:0030496 midbody
GO:0031965 nuclear membrane
GO:0034993 meiotic nuclear membrane microtubule tethering complex
GO:0042692 muscle cell differentiation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043197 dendritic spine
GO:0044327 dendritic spine head
GO:0045211 postsynaptic membrane
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0048471 perinuclear region of cytoplasm
GO:0048814 regulation of dendrite morphogenesis
GO:0051015 actin filament binding
GO:0051642 centrosome localization
GO:0061886 negative regulation of mini excitatory postsynaptic potential
GO:0090292 nuclear matrix anchoring at nuclear membrane
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization
GO:0140444 cytoskeleton-nuclear membrane anchor activity
GO:1902017 regulation of cilium assembly
GO:1903353 regulation of nucleus organization
GO:2001054 negative regulation of mesenchymal cell apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus envelope
Nucleus outer membrane

Domains

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DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001715 Calponin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR012315 KASH domainDomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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