Entity Details

Primary name ABCG2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TMS5
EntryNameABCG2_MOUSE
FullNameBroad substrate specificity ATP-binding cassette transporter ABCG2
TaxID10090
Evidenceevidence at protein level
Length657
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesAbcg2

GO terms

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GOName
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0008092 cytoskeletal protein binding
GO:0008514 organic anion transmembrane transporter activity
GO:0008559 ABC-type xenobiotic transporter activity
GO:0015143 urate transmembrane transporter activity
GO:0015225 biotin transmembrane transporter activity
GO:0015562 efflux transmembrane transporter activity
GO:0015711 organic anion transport
GO:0015747 urate transport
GO:0015878 biotin transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0019389 glucuronoside metabolic process
GO:0031526 brush border membrane
GO:0031966 mitochondrial membrane
GO:0032217 riboflavin transmembrane transporter activity
GO:0032218 riboflavin transport
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042887 amide transmembrane transporter activity
GO:0042910 xenobiotic transmembrane transporter activity
GO:0045121 membrane raft
GO:0046415 urate metabolic process
GO:0055085 transmembrane transport
GO:0060136 embryonic process involved in female pregnancy
GO:0065003 protein-containing complex assembly
GO:0070633 transepithelial transport
GO:0097744 urate salt excretion
GO:0098591 external side of apical plasma membrane
GO:0140115 export across plasma membrane
GO:1904479 negative regulation of intestinal absorption
GO:1990748 cellular detoxification
GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane
GO:1990962 xenobiotic transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Mitochondrion membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR013525 ABC-2 type transporterDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030256 ATP-binding cassette subfamily G member 2FamilyFamily
IPR043926 ABC transporter family G domainDomainDomain

Diseases

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Interactions

0 interactions

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