Entity Details

Primary name RFX4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TNK1
EntryNameRFX4_MOUSE
FullNameTranscription factor RFX4
TaxID10090
Evidenceevidence at protein level
Length735
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesRfx4

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0021516 dorsal spinal cord development
GO:0021537 telencephalon development
GO:0021696 cerebellar cortex morphogenesis
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0030900 forebrain development
GO:0030901 midbrain development
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060271 cilium assembly
GO:0070613 regulation of protein processing
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003150 DNA-binding RFX-type winged-helix domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR039779 RFX-like DNA-binding proteinFamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
RFX4_MOUSETFE2_MOUSEBioGRID, IntAct20211142 details
RFX4_MOUSESSBP3_MOUSEBioGRID, IntAct20211142 details
RFX4_MOUSEGPS2_MOUSEBioGRID18218630 details