Entity Details

Primary name ACTN1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TPR4
EntryNameACTN1_MOUSE
FullNameAlpha-actinin-1
TaxID10090
Evidenceevidence at protein level
Length892
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesActn1

GO terms

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GOName
GO:0001725 stress fiber
GO:0001726 ruffle
GO:0003725 double-stranded RNA binding
GO:0005178 integrin binding
GO:0005509 calcium ion binding
GO:0005519 cytoskeletal regulatory protein binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0005911 cell-cell junction
GO:0005916 fascia adherens
GO:0005925 focal adhesion
GO:0007015 actin filament organization
GO:0017166 vinculin binding
GO:0019904 protein domain specific binding
GO:0030017 sarcomere
GO:0030018 Z disc
GO:0030054 cell junction
GO:0030141 secretory granule
GO:0030220 platelet formation
GO:0030374 nuclear receptor coactivator activity
GO:0030863 cortical cytoskeleton
GO:0030865 cortical cytoskeleton organization
GO:0032127 dense core granule membrane
GO:0036344 platelet morphogenesis
GO:0042803 protein homodimerization activity
GO:0042995 cell projection
GO:0043197 dendritic spine
GO:0044325 transmembrane transporter binding
GO:0048041 focal adhesion assembly
GO:0051015 actin filament binding
GO:0051017 actin filament bundle assembly
GO:0051271 negative regulation of cellular component movement
GO:0051639 actin filament network formation
GO:0098978 glutamatergic synapse
GO:0099186 structural constituent of postsynapse

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001715 Calponin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR014837 EF-hand, Ca insensitiveDomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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