Entity Details

Primary name APTX_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TQC5
EntryNameAPTX_MOUSE
FullNameAprataxin
TaxID10090
Evidenceevidence at protein level
Length342
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesAptx

GO terms

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GOName
GO:0000012 single strand break repair
GO:0000785 chromatin
GO:0003682 chromatin binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0003725 double-stranded RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006266 DNA ligation
GO:0006302 double-strand break repair
GO:0006974 cellular response to DNA damage stimulus
GO:0008967 phosphoglycolate phosphatase activity
GO:0030983 mismatched DNA binding
GO:0031647 regulation of protein stability
GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity
GO:0042542 response to hydrogen peroxide
GO:0046403 polynucleotide 3'-phosphatase activity
GO:0046872 metal ion binding
GO:0047485 protein N-terminus binding
GO:0051219 phosphoprotein binding
GO:0120108 DNA-3'-diphospho-5'-guanosine diphosphatase
GO:1990165 single-strand break-containing DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000253 Forkhead-associated (FHA) domainDomainDomain
IPR008984 SMAD/FHA domain superfamilyFamilyHomologous superfamily
IPR011146 HIT-like domainDomainDomain
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR019808 Histidine triad, conserved siteSiteConserved site
IPR026963 Aprataxin-likeFamilyFamily
IPR032566 Aprataxin, C2HE/C2H2/C2HC zinc fingerDomainDomain
IPR036265 HIT-like superfamilyFamilyHomologous superfamily
IPR041388 PNK, FHA domainDomainDomain

Diseases

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Interactions

0 interactions

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