Entity Details

Primary name OTUB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TQI3
EntryNameOTUB1_MOUSE
FullNameUbiquitin thioesterase OTUB1
TaxID10090
Evidenceevidence at protein level
Length271
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesOtub1

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0016579 protein deubiquitination
GO:0019784 NEDD8-specific protease activity
GO:0043130 ubiquitin binding
GO:0071108 protein K48-linked deubiquitination
GO:0071347 cellular response to interleukin-1
GO:0101005 deubiquitinase activity
GO:1901315 negative regulation of histone H2A K63-linked ubiquitination
GO:2000780 negative regulation of double-strand break repair

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR003323 OTU domainDomainDomain
IPR016615 Ubiquitin thioesterase OtubainFamilyFamily
IPR019400 Peptidase C65, otubainFamilyFamily
IPR030298 Ubiquitin thioesterase OTUB1FamilyFamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily
IPR042467 Peptidase C65, otubain, subdomain 2FamilyHomologous superfamily
IPR042468 Peptidase C65, otubain, subdomain 1FamilyHomologous superfamily

Diseases

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