Entity Details

Primary name EXOS3_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TQK4
EntryNameEXOS3_MOUSE
FullNameExosome complex component RRP40
TaxID10090
Evidenceevidence at protein level
Length274
SequenceStatuscomplete
DateCreated2004-04-26
DateModified2021-06-02

Ontological Relatives

GenesExosc3

GO terms

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GOName
GO:0000176 nuclear exosome (RNase complex)
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 RNA binding
GO:0004527 exonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006364 rRNA processing
GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0034475 U4 snRNA 3'-end processing
GO:0035327 transcriptionally active chromatin
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0045006 DNA deamination
GO:0045190 isotype switching
GO:0045830 positive regulation of isotype switching
GO:0071034 CUT catabolic process
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process
GO:0071049 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
GO:0071051 polyadenylation-dependent snoRNA 3'-end processing

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004088 K Homology domain, type 1DomainDomain
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR026699 Exosome complex RNA-binding protein 1/RRP40/RRP4FamilyFamily
IPR036612 K Homology domain, type 1 superfamilyFamilyHomologous superfamily
IPR037319 Rrp40, S1 domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
EXOS3_MOUSEAICDA_MOUSEBioGRID, IntAct21255825 23964096 details