Entity Details

Primary name MCPH1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ7TT79
EntryNameMCPH1_MOUSE
FullNameMicrocephalin
TaxID10090
Evidenceevidence at protein level
Length822
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesMcph1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000132 establishment of mitotic spindle orientation
GO:0000278 mitotic cell cycle
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0010468 regulation of gene expression
GO:0021987 cerebral cortex development
GO:0042802 identical protein binding
GO:0043549 regulation of kinase activity
GO:0046605 regulation of centrosome cycle
GO:0050727 regulation of inflammatory response
GO:0060348 bone development
GO:0060623 regulation of chromosome condensation
GO:0071539 protein localization to centrosome
GO:0097150 neuronal stem cell population maintenance

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001357 BRCT domainDomainDomain
IPR022047 Microcephalin-likeFamilyFamily
IPR029504 Microcephalin, mammalFamilyFamily
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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