Entity Details

Primary name CASP6_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08738
EntryNameCASP6_MOUSE
FullNameCaspase-6
TaxID10090
Evidenceevidence at protein level
Length276
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCasp6

GO terms

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GOName
GO:0002525 acute inflammatory response to non-antigenic stimulus
GO:0004175 endopeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0007413 axonal fasciculation
GO:0009749 response to glucose
GO:0010039 response to iron ion
GO:0030424 axon
GO:0030855 epithelial cell differentiation
GO:0034097 response to cytokine
GO:0042542 response to hydrogen peroxide
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0046670 positive regulation of retinal cell programmed cell death
GO:0072734 cellular response to staurosporine
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR002138 Peptidase C14, caspase non-catalytic subunit p10DomainDomain
IPR002398 Peptidase C14 familyFamilyFamily
IPR015917 Peptidase C14A, caspase catalytic domainDomainDomain
IPR016129 Peptidase family C14A, His active siteSiteActive site
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033139 Peptidase family C14A, cysteine active siteSiteActive site
IPR037554 Caspase-6FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CASP6_MOUSEIRAK3_MOUSEBioGRID21098228 32325033 details
CASP6_MOUSECRYAB_MOUSEBioGRID16439475 details