Entity Details

Primary name UBR5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ80TP3
EntryNameUBR5_MOUSE
FullNameE3 ubiquitin-protein ligase UBR5
TaxID10090
Evidenceevidence at protein level
Length2792
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesUbr5

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0008270 zinc ion binding
GO:0010628 positive regulation of gene expression
GO:0031647 regulation of protein stability
GO:0032700 negative regulation of interleukin-17 production
GO:0032991 protein-containing complex
GO:0034450 ubiquitin-ubiquitin ligase activity
GO:0042307 positive regulation of protein import into nucleus
GO:0043130 ubiquitin binding
GO:0048471 perinuclear region of cytoplasm
GO:0050847 progesterone receptor signaling pathway
GO:0061630 ubiquitin protein ligase activity
GO:0070936 protein K48-linked ubiquitination
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901315 negative regulation of histone H2A K63-linked ubiquitination
GO:2000779 regulation of double-strand break repair
GO:2000780 negative regulation of double-strand break repair

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000569 HECT domainDomainDomain
IPR002004 Polyadenylate-binding protein/Hyperplastic disc proteinDomainDomain
IPR003126 Zinc finger, UBR-typeDomainDomain
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIFamilyHomologous superfamily
IPR024725 E3 ubiquitin ligase EDD, ubiquitin-associated domainDomainDomain
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR036053 PABC (PABP) domainFamilyHomologous superfamily

Diseases

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Interactions

5 interactions