Entity Details

Primary name MADD_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ80U28
EntryNameMADD_MOUSE
FullNameMAP kinase-activating death domain protein
TaxID10090
Evidenceevidence at protein level
Length1577
SequenceStatuscomplete
DateCreated2007-02-20
DateModified2021-06-02

Ontological Relatives

GenesMadd

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016021 integral component of membrane
GO:0032483 regulation of Rab protein signal transduction
GO:0042981 regulation of apoptotic process
GO:0045202 synapse
GO:0048490 anterograde synaptic vesicle transport
GO:0051726 regulation of cell cycle
GO:0060125 negative regulation of growth hormone secretion
GO:0097194 execution phase of apoptosis
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902277 negative regulation of pancreatic amylase secretion
GO:1904115 axon cytoplasm
GO:2001234 negative regulation of apoptotic signaling pathway
GO:2001236 regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001194 cDENN domainDomainDomain
IPR005112 dDENN domainDomainDomain
IPR005113 uDENN domainDomainDomain
IPR037516 Tripartite DENN domainDomainDomain
IPR039980 MAP kinase-activating death domain proteinFamilyFamily
IPR043153 DENN domain, C-terminal lobeFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MADD_MOUSE1433Z_MOUSEBioGRID16959763 details