Entity Details

Primary name TCAM1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ80UF7
EntryNameTCAM1_MOUSE
FullNameTIR domain-containing adapter molecule 1
TaxID10090
Evidenceevidence at protein level
Length732
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesTicam1

GO terms

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GOName
GO:0002281 macrophage activation involved in immune response
GO:0002735 positive regulation of myeloid dendritic cell cytokine production
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0005739 mitochondrion
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0006954 inflammatory response
GO:0010508 positive regulation of autophagy
GO:0010628 positive regulation of gene expression
GO:0019901 protein kinase binding
GO:0030890 positive regulation of B cell proliferation
GO:0031398 positive regulation of protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032092 positive regulation of protein binding
GO:0032481 positive regulation of type I interferon production
GO:0032496 response to lipopolysaccharide
GO:0032722 positive regulation of chemokine production
GO:0032728 positive regulation of interferon-beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032816 positive regulation of natural killer cell activation
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043254 regulation of protein-containing complex assembly
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0050871 positive regulation of B cell activation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051607 defense response to virus
GO:0071222 cellular response to lipopolysaccharide
GO:0097190 apoptotic signaling pathway
GO:0097342 ripoptosome
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus
GO:1900017 positive regulation of cytokine production involved in inflammatory response

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Mitochondrion

Domains

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DomainNameCategoryType
IPR017278 TIR domain-containing adapter molecule 1FamilyFamily
IPR025735 RHIM domainDomainDomain
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR040886 TRIF, N-terminalDomainDomain

Diseases

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