Entity Details

Primary name HCD2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08756
EntryNameHCD2_MOUSE
FullName3-hydroxyacyl-CoA dehydrogenase type-2
TaxID10090
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-04-07

Ontological Relatives

GO terms

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GOName
GO:0000049 tRNA binding
GO:0001540 amyloid-beta binding
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005496 steroid binding
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005783 endoplasmic reticulum
GO:0006550 isoleucine catabolic process
GO:0006635 fatty acid beta-oxidation
GO:0006699 bile acid biosynthetic process
GO:0007005 mitochondrion organization
GO:0008207 C21-steroid hormone metabolic process
GO:0008209 androgen metabolic process
GO:0008210 estrogen metabolic process
GO:0008709 cholate 7-alpha-dehydrogenase activity
GO:0018454 acetoacetyl-CoA reductase activity
GO:0030283 testosterone dehydrogenase [NAD(P)] activity
GO:0030331 estrogen receptor binding
GO:0030678 mitochondrial ribonuclease P complex
GO:0042645 mitochondrial nucleoid
GO:0042802 identical protein binding
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
GO:0047035 testosterone dehydrogenase (NAD+) activity
GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity
GO:0051287 NAD binding
GO:0051289 protein homotetramerization
GO:0062173 brexanolone metabolic process
GO:0070901 mitochondrial tRNA methylation
GO:0097745 mitochondrial tRNA 5'-end processing
GO:0106281 chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity
GO:0106282 isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
GO:0106283 ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
GO:1990180 mitochondrial tRNA 3'-end processing

Subcellular Location

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Subcellular Location
Mitochondrion
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HCD2_MOUSESUMF1_HUMANMINT17446859 details