Entity Details

Primary name UBE3A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08759
EntryNameUBE3A_MOUSE
FullNameUbiquitin-protein ligase E3A
TaxID10090
Evidenceevidence at protein level
Length870
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesUbe3a

GO terms

Show/Hide Table
GOName
GO:0000502 proteasome complex
GO:0001541 ovarian follicle development
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016567 protein ubiquitination
GO:0030521 androgen receptor signaling pathway
GO:0031398 positive regulation of protein ubiquitination
GO:0032570 response to progesterone
GO:0035037 sperm entry
GO:0042220 response to cocaine
GO:0042542 response to hydrogen peroxide
GO:0042752 regulation of circadian rhythm
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048511 rhythmic process
GO:0050847 progesterone receptor signaling pathway
GO:0051865 protein autoubiquitination
GO:0060736 prostate gland growth
GO:0061002 negative regulation of dendritic spine morphogenesis
GO:0061630 ubiquitin protein ligase activity
GO:0070936 protein K48-linked ubiquitination
GO:1905528 positive regulation of Golgi lumen acidification
GO:1990416 cellular response to brain-derived neurotrophic factor stimulus
GO:2000058 regulation of ubiquitin-dependent protein catabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000569 HECT domainDomainDomain
IPR017134 Ubiquitin-protein ligase E3AFamilyFamily
IPR032353 Ubiquitin-protein ligase E3A, N-terminal zinc-binding domainDomainDomain
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR042556 Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table