Entity Details

Primary name PTPRF_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2A8L5
EntryNamePTPRF_MOUSE
FullNameReceptor-type tyrosine-protein phosphatase F
TaxID10090
Evidenceevidence at protein level
Length1898
SequenceStatuscomplete
DateCreated2009-04-14
DateModified2021-06-02

Ontological Relatives

GenesPtprf

GO terms

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GOName
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005158 insulin receptor binding
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007399 nervous system development
GO:0008201 heparin binding
GO:0008285 negative regulation of cell population proliferation
GO:0010975 regulation of neuron projection development
GO:0016020 membrane
GO:0016477 cell migration
GO:0030426 growth cone
GO:0030971 receptor tyrosine kinase binding
GO:0031102 neuron projection regeneration
GO:0031345 negative regulation of cell projection organization
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035373 chondroitin sulfate proteoglycan binding
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042301 phosphate ion binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043525 positive regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0048679 regulation of axon regeneration
GO:0050775 positive regulation of dendrite morphogenesis
GO:0050803 regulation of synapse structure or activity
GO:0050839 cell adhesion molecule binding
GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway
GO:0060076 excitatory synapse
GO:0099061 integral component of postsynaptic density membrane
GO:0099175 regulation of postsynapse organization
GO:0099560 synaptic membrane adhesion
GO:1900121 negative regulation of receptor binding

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions