Entity Details

Primary name PRDX4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08807
EntryNamePRDX4_MOUSE
FullNamePeroxiredoxin-4
TaxID10090
Evidenceevidence at protein level
Length274
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPrdx4

GO terms

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GOName
GO:0004601 peroxidase activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005790 smooth endoplasmic reticulum
GO:0005829 cytosol
GO:0006979 response to oxidative stress
GO:0007283 spermatogenesis
GO:0008584 male gonad development
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0022417 protein maturation by protein folding
GO:0030198 extracellular matrix organization
GO:0045454 cell redox homeostasis
GO:0051920 peroxiredoxin activity
GO:0072593 reactive oxygen species metabolic process
GO:2000255 negative regulation of male germ cell proliferation

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum

Domains

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DomainNameCategoryType
IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidantDomainDomain
IPR013766 Thioredoxin domainDomainDomain
IPR019479 Peroxiredoxin, C-terminalDomainDomain
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PRDX4_MOUSETXND5_HUMANDIP24462249 details
PRDX4_MOUSEITA2B_MOUSEBioGRID30333137 details