Entity Details

Primary name KDM5B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ80Y84
EntryNameKDM5B_MOUSE
FullNameLysine-specific demethylase 5B
TaxID10090
Evidenceevidence at protein level
Length1544
SequenceStatuscomplete
DateCreated2007-06-26
DateModified2021-06-02

Ontological Relatives

GenesKdm5b

GO terms

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GOName
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006338 chromatin remodeling
GO:0007338 single fertilization
GO:0008270 zinc ion binding
GO:0009791 post-embryonic development
GO:0010628 positive regulation of gene expression
GO:0032452 histone demethylase activity
GO:0032453 histone demethylase activity (H3-K4 specific)
GO:0033601 positive regulation of mammary gland epithelial cell proliferation
GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 histone H3-K4 demethylation
GO:0042393 histone binding
GO:0042752 regulation of circadian rhythm
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048511 rhythmic process
GO:0051213 dioxygenase activity
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060763 mammary duct terminal end bud growth
GO:0060992 response to fungicide
GO:0061038 uterus morphogenesis
GO:0070306 lens fiber cell differentiation
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000864 regulation of estradiol secretion

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001606 ARID DNA-binding domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003347 JmjC domainDomainDomain
IPR003349 JmjN domainDomainDomain
IPR004198 Zinc finger, C5HC2-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013637 Lysine-specific demethylase-like domainDomainDomain
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR036431 ARID DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
KDM5B_MOUSEMO4L1_MOUSEBioGRID, MINT21448134 details