Entity Details

Primary name RGS2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO08849
EntryNameRGS2_MOUSE
FullNameRegulator of G-protein signaling 2
TaxID10090
Evidenceevidence at transcript level
Length211
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesRgs2

GO terms

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GOName
GO:0001965 G-protein alpha-subunit binding
GO:0001975 response to amphetamine
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007049 cell cycle
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007283 spermatogenesis
GO:0007420 brain development
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0009898 cytoplasmic side of plasma membrane
GO:0010519 negative regulation of phospholipase activity
GO:0010614 negative regulation of cardiac muscle hypertrophy
GO:0010976 positive regulation of neuron projection development
GO:0017148 negative regulation of translation
GO:0030728 ovulation
GO:0043005 neuron projection
GO:0043407 negative regulation of MAP kinase activity
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045471 response to ethanol
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0048487 beta-tubulin binding
GO:0050873 brown fat cell differentiation
GO:0055119 relaxation of cardiac muscle
GO:0060087 relaxation of vascular associated smooth muscle
GO:0060135 maternal process involved in female pregnancy
GO:0060452 positive regulation of cardiac muscle contraction
GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development
GO:0140194 negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process
GO:1900924 negative regulation of glycine import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR016137 RGS domainDomainDomain
IPR024066 RGS, subdomain 1/3FamilyHomologous superfamily
IPR034947 Regulator of G-protein signalling 2FamilyFamily
IPR036305 RGS domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
RGS2_MOUSENEB2_MOUSEMINT17464283 details
RGS2_MOUSELRRK2_MOUSEIntAct24794857 details