Entity Details

Primary name SHAN2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ80Z38
EntryNameSHAN2_MOUSE
FullNameSH3 and multiple ankyrin repeat domains protein 2
TaxID10090
Evidenceevidence at protein level
Length1476
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesShank2

GO terms

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GOName
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005883 neurofilament
GO:0005886 plasma membrane
GO:0007416 synapse assembly
GO:0007612 learning
GO:0007613 memory
GO:0008022 protein C-terminus binding
GO:0008284 positive regulation of cell population proliferation
GO:0014069 postsynaptic density
GO:0016324 apical plasma membrane
GO:0017124 SH3 domain binding
GO:0030160 synaptic receptor adaptor activity
GO:0030426 growth cone
GO:0030534 adult behavior
GO:0031526 brush border membrane
GO:0032279 asymmetric synapse
GO:0035176 social behavior
GO:0035255 ionotropic glutamate receptor binding
GO:0035331 negative regulation of hippo signaling
GO:0035640 exploration behavior
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0048786 presynaptic active zone
GO:0048854 brain morphogenesis
GO:0050807 regulation of synapse organization
GO:0051124 synaptic assembly at neuromuscular junction
GO:0051968 positive regulation of synaptic transmission, glutamatergic
GO:0060170 ciliary membrane
GO:0060291 long-term synaptic potentiation
GO:0060292 long-term synaptic depression
GO:0060997 dendritic spine morphogenesis
GO:0060999 positive regulation of dendritic spine development
GO:0071625 vocalization behavior
GO:0097107 postsynaptic density assembly
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098919 structural constituent of postsynaptic density
GO:0098978 glutamatergic synapse
GO:0099562 maintenance of postsynaptic density structure
GO:2000311 regulation of AMPA receptor activity
GO:2000463 positive regulation of excitatory postsynaptic potential

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell junction
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR001660 Sterile alpha motif domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR041489 PDZ domain 6DomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SHAN2_MOUSENMDE2_MOUSEBioGRID, IntAct10862698 16635246 details
SHAN2_MOUSEPDE4D_MOUSEIntAct17244609 details