Entity Details

Primary name NANOG_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ80Z64
EntryNameNANOG_MOUSE
FullNameHomeobox protein NANOG
TaxID10090
Evidenceevidence at protein level
Length305
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesNanog

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001010 RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001710 mesodermal cell fate commitment
GO:0001714 endodermal cell fate specification
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell population proliferation
GO:0008406 gonad development
GO:0009880 embryonic pattern specification
GO:0010033 response to organic substance
GO:0010454 negative regulation of cell fate commitment
GO:0010468 regulation of gene expression
GO:0017145 stem cell division
GO:0019827 stem cell population maintenance
GO:0030514 negative regulation of BMP signaling pathway
GO:0032526 response to retinoic acid
GO:0035019 somatic stem cell population maintenance
GO:0042664 negative regulation of endodermal cell fate specification
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0043697 cell dedifferentiation
GO:0045595 regulation of cell differentiation
GO:0045596 negative regulation of cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045931 positive regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048863 stem cell differentiation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000035 regulation of stem cell division
GO:2000648 positive regulation of stem cell proliferation

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site

Diseases

Show/Hide Table

Interactions

57 interactions

InteractorPartnerSourcesPublicationsLink
NANOG_MOUSEPO5F1_MOUSEBioGRID, DIP, IntAct17093407 18436640 18454139 20362541 22036565 23395962 23444350 details
NANOG_MOUSEPIN1_MOUSEBioGRID, DIP20622153 details
NANOG_MOUSENFKB2_MOUSEBioGRID18223644 details
NANOG_MOUSETF65_MOUSEBioGRID18223644 details
NANOG_MOUSEMK03_MOUSEBioGRID24793005 details
NANOG_MOUSEMK01_MOUSEBioGRID24793005 details
NANOG_MOUSESALL4_MOUSEBioGRID, DIP, IntAct, MINT16840789 17093407 18436640 18454139 19060217 21589869 23395962 23892456 details
NANOG_MOUSERIF1_MOUSEBioGRID, IntAct17093407 18454139 21589869 details
NANOG_MOUSETIF1B_MOUSEBioGRID, IntAct17093407 18454139 21589869 details
NANOG_MOUSENAC1_MOUSEIntAct17093407 details
NANOG_MOUSENR0B1_MOUSEBioGRID, DIP, IntAct, MINT17093407 18436640 20362541 21589869 23892456 details
NANOG_MOUSEZN281_MOUSEBioGRID, DIP, IntAct, MINT17093407 18436640 21589869 23892456 details
NANOG_MOUSEZMYM2_MOUSEBioGRID, DIP, IntAct, MINT17093407 18436640 23892456 details
NANOG_MOUSEERR2_MOUSEBioGRID, IntAct17093407 18454139 23892456 details
NANOG_MOUSEHDAC2_MOUSEBioGRID, IntAct17093407 18454139 23395962 details
NANOG_MOUSESOX2_MOUSEBioGRID, IntAct, MINT18454139 21589869 21962512 23892456 31077711 details
NANOG_MOUSEMTA2_MOUSEBioGRID, MINT18454139 21589869 23395962 23892456 details
NANOG_MOUSENACC1_MOUSEBioGRID, DIP, MINT17093407 18436640 21589869 23395962 23892456 details
NANOG_MOUSEZN609_MOUSEBioGRID, MINT23395962 23892456 details
NANOG_MOUSEBRCA2_MOUSEBioGRID, MINT23395962 23892456 details
NANOG_MOUSESIN3A_MOUSEBioGRID, MINT18454139 23892456 details
NANOG_MOUSESMC3_MOUSEBioGRID, MINT23395962 23892456 details
NANOG_MOUSEKDM1A_MOUSEBioGRID, MINT18454139 23892456 details
NANOG_MOUSEP66A_MOUSEBioGRID, MINT18454139 23395962 23892456 details
NANOG_MOUSEP66B_MOUSEBioGRID, MINT18454139 23892456 details
NANOG_MOUSENANOG_MOUSEBioGRID, DIP18223644 18436640 21589869 23892456 31077711 details
NANOG_MOUSEPIN1_HUMANDIP20622153 details
NANOG_MOUSEUBB_MOUSEDIP20622153 details
NANOG_MOUSEUBC_MOUSEDIP20622153 details
NANOG_MOUSERS27A_MOUSEDIP20622153 details
NANOG_MOUSERL40_MOUSEDIP20622153 details
NANOG_MOUSEHDAC1_MOUSEBioGRID18454139 21589869 details
NANOG_MOUSEPML_MOUSEBioGRID18454139 21589869 details
NANOG_MOUSESMCA2_MOUSEBioGRID18454139 details
NANOG_MOUSESMCA4_MOUSEBioGRID18454139 details
NANOG_MOUSEMBD3_MOUSEBioGRID18454139 21589869 23892456 details
NANOG_MOUSERBBP7_MOUSEBioGRID18454139 details
NANOG_MOUSERAD21_MOUSEBioGRID21589869 details
NANOG_MOUSESTAG1_MOUSEBioGRID21589869 details
NANOG_MOUSEWDR18_MOUSEBioGRID21589869 23395962 details
NANOG_MOUSERELB_MOUSEBioGRID18223644 details
NANOG_MOUSEARI3B_MOUSEBioGRID23395962 23892456 details
NANOG_MOUSEMTA3_MOUSEBioGRID23395962 23892456 details
NANOG_MOUSEEMSY_MOUSEBioGRID23395962 23892456 details
NANOG_MOUSEFBXW4_MOUSEBioGRID24793005 details
NANOG_MOUSEFBXW5_MOUSEBioGRID24793005 details
NANOG_MOUSEFBXW8_MOUSEBioGRID24793005 details
NANOG_MOUSEH4_MOUSEBioGRID23798425 details
NANOG_MOUSECTNB1_MOUSEBioGRID23444350 details
NANOG_MOUSEJHD2C_MOUSEBioGRID23395962 details
NANOG_MOUSENCOR2_MOUSEBioGRID23395962 details
NANOG_MOUSEHNRPM_MOUSEBioGRID23395962 details
NANOG_MOUSEMTREX_MOUSEBioGRID23395962 details
NANOG_MOUSELMNB1_MOUSEBioGRID23395962 details
NANOG_MOUSEUBP21_MOUSEBioGRID27886188 29263902 details
NANOG_MOUSESPOP_MOUSEBioGRID30595535 details
NANOG_MOUSERACK1_MOUSEBioGRID30809310 details