Entity Details

Primary name DLG1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ811D0
EntryNameDLG1_MOUSE
FullNameDisks large homolog 1
TaxID10090
Evidenceevidence at protein level
Length905
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesDlg1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001771 immunological synapse formation
GO:0001772 immunological synapse
GO:0001935 endothelial cell proliferation
GO:0002088 lens development in camera-type eye
GO:0005604 basement membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005902 microvillus
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0007015 actin filament organization
GO:0007268 chemical synaptic transmission
GO:0008022 protein C-terminus binding
GO:0008104 protein localization
GO:0008284 positive regulation of cell population proliferation
GO:0008360 regulation of cell shape
GO:0009898 cytoplasmic side of plasma membrane
GO:0009925 basal plasma membrane
GO:0014069 postsynaptic density
GO:0015459 potassium channel regulator activity
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0019894 kinesin binding
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0030054 cell junction
GO:0030165 PDZ domain binding
GO:0030315 T-tubule
GO:0030425 dendrite
GO:0030432 peristalsis
GO:0030672 synaptic vesicle membrane
GO:0030838 positive regulation of actin filament polymerization
GO:0030866 cortical actin cytoskeleton organization
GO:0030953 astral microtubule organization
GO:0031253 cell projection membrane
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0031579 membrane raft organization
GO:0031594 neuromuscular junction
GO:0031641 regulation of myelination
GO:0032147 activation of protein kinase activity
GO:0032880 regulation of protein localization
GO:0033268 node of Ranvier
GO:0033270 paranode region of axon
GO:0034629 cellular protein-containing complex localization
GO:0035255 ionotropic glutamate receptor binding
GO:0035748 myelin sheath abaxonal region
GO:0040018 positive regulation of multicellular organism growth
GO:0042110 T cell activation
GO:0042130 negative regulation of T cell proliferation
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0042982 amyloid precursor protein metabolic process
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043113 receptor clustering
GO:0043219 lateral loop
GO:0043268 positive regulation of potassium ion transport
GO:0043622 cortical microtubule organization
GO:0044325 transmembrane transporter binding
GO:0045121 membrane raft
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0048608 reproductive structure development
GO:0048639 positive regulation of developmental growth
GO:0048704 embryonic skeletal system morphogenesis
GO:0048729 tissue morphogenesis
GO:0048745 smooth muscle tissue development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051660 establishment of centrosome localization
GO:0051898 negative regulation of protein kinase B signaling
GO:0060022 hard palate development
GO:0060090 molecular adaptor activity
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0070830 bicellular tight junction assembly
GO:0072659 protein localization to plasma membrane
GO:0097016 L27 domain binding
GO:0097025 MPP7-DLG1-LIN7 complex
GO:0097060 synaptic membrane
GO:0097120 receptor localization to synapse
GO:0098609 cell-cell adhesion
GO:0098839 postsynaptic density membrane
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0098919 structural constituent of postsynaptic density
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane
GO:1902473 regulation of protein localization to synapse
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1903286 regulation of potassium ion import
GO:1903753 negative regulation of p38MAPK cascade
GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1903764 regulation of potassium ion export across plasma membrane
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell junction
Cell membrane
Cytoplasm
Endoplasmic reticulum membrane
Membrane

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR004172 L27 domainDomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR015143 L27-1DomainDomain
IPR016313 Disks large 1-likeFamilyFamily
IPR019583 PDZ-associated domain of NMDA receptorsDomainDomain
IPR019590 Disks large homologue 1, N-terminal PEST domainDomainDomain
IPR020590 Guanylate kinase, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036892 L27 domain superfamilyFamilyHomologous superfamily

Diseases

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