Entity Details

Primary name IREB2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ811J3
EntryNameIREB2_MOUSE
FullNameIron-responsive element-binding protein 2
TaxID10090
Evidenceevidence at protein level
Length963
SequenceStatuscomplete
DateCreated2005-05-24
DateModified2021-06-02

Ontological Relatives

GenesIreb2

GO terms

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GOName
GO:0001069 regulatory region RNA binding
GO:0003723 RNA binding
GO:0003994 aconitate hydratase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006099 tricarboxylic acid cycle
GO:0006101 citrate metabolic process
GO:0006417 regulation of translation
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006879 cellular iron ion homeostasis
GO:0009791 post-embryonic development
GO:0010041 response to iron(III) ion
GO:0010468 regulation of gene expression
GO:0017148 negative regulation of translation
GO:0030316 osteoclast differentiation
GO:0030350 iron-responsive element binding
GO:0030371 translation repressor activity
GO:0030424 axon
GO:0034101 erythrocyte homeostasis
GO:0043025 neuronal cell body
GO:0046872 metal ion binding
GO:0050892 intestinal absorption
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0055072 iron ion homeostasis
GO:0071283 cellular response to iron(III) ion
GO:0071287 cellular response to manganese ion
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0072705 cellular response to mercaptoethanol
GO:0090650 cellular response to oxygen-glucose deprivation

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domainDomainDomain
IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domainDomainDomain
IPR006249 Aconitase/Iron-responsive element-binding protein 2FamilyFamily
IPR015928 Aconitase/3-isopropylmalate dehydratase, swivelFamilyHomologous superfamily
IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3FamilyHomologous superfamily
IPR018136 Aconitase family, 4Fe-4S cluster binding siteSiteBinding site
IPR029755 Iron regulatory protein 2FamilyFamily
IPR036008 Aconitase, iron-sulfur domainFamilyHomologous superfamily
IPR044137 Aconitase A, swivel domainDomainDomain

Diseases

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Interactions

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