Entity Details

Primary name TXNIP_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ8BG60
EntryNameTXNIP_MOUSE
FullNameThioredoxin-interacting protein
TaxID10090
Evidenceevidence at protein level
Length397
SequenceStatuscomplete
DateCreated2006-10-03
DateModified2021-06-02

Ontological Relatives

GenesTxnip

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0004857 enzyme inhibitor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0006606 protein import into nucleus
GO:0006979 response to oxidative stress
GO:0007049 cell cycle
GO:0009612 response to mechanical stimulus
GO:0009749 response to glucose
GO:0015031 protein transport
GO:0030216 keratinocyte differentiation
GO:0031625 ubiquitin protein ligase binding
GO:0032355 response to estradiol
GO:0032570 response to progesterone
GO:0042127 regulation of cell population proliferation
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0043065 positive regulation of apoptotic process
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0051592 response to calcium ion
GO:0051782 negative regulation of cell division
GO:0071228 cellular response to tumor cell

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR011021 Arrestin-like, N-terminalDomainDomain
IPR011022 Arrestin C-terminal-like domainDomainDomain
IPR014752 Arrestin-like, C-terminalFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TXNIP_MOUSETHIO_HUMANBioGRID10843682 16766796 details
TXNIP_MOUSEANM1_MOUSEIntAct25003952 details